Abstract: This paper mainly introduces the seismic risk calculation and data processing in the survey of earthquake disaster risk work. We discuss the establishment of standard grid, data processing, batch mapping and the generation of word documents based on ArcGIS software, Matlab and Python programs. Taking the seismic risk calculation and data processing in Hunan province as an example, we completed the seismic risk calculation and site adjustment of approximately 280,000 calculation points in 30 second standard grid, and classified the seismic risk. Seismic risk maps of 14 cities and 122 counties in Hunan province were plotted in batches, as well as word reports were generated in batches. The paper detailed processing steps and efficiency were analyzed. We found that the use of ArcGIS software platform for batch drawing, combined with Matlab and Python program code to generate vector data shape files and process word documents, was time-saving, efficient and highly repeatable, which can provide a reference for researchers engaged in seismic risk calculation work.