Abstract: In this paper, a GIS-based method for seismic risk zoning evaluation is established. The paper selected five evaluation factors, such as earthquake magnitude, seismic frequency, fault length, fracture age and fracture properties,and put forward corresponding quantitative processing methods for these elements according to the characteristics of them, and finally, obtained evaluation results by overlay analysis according to the weight of evaluation elements. In this paper, this method is used to evaluate the seismic hazard zonation in Xigaze region. The results show that the high-risk areas in the Xigaze area are mainly distributed in the Xietongmen-Lazi area and the northeastern part of Nanmulin, the seismic hazard areas are mainly distributed in the outer edge of high-risk areas, Xigaze urban area and a small area of Nanmulin County, other regions are sub-safe, medium-level safe or safe areas, which can provide reference for land planning in Xigaze area.